incidence of gestational diabetes mellitus (GDM) has more than doubled in

incidence of gestational diabetes mellitus (GDM) has more than doubled in TOK-001 (Galeterone) the past decade1 and affects at least 7% of all pregnancies or 200 0 ladies per year in the US. in T2DM Rabbit Polyclonal to TNFRSF6B. risk among the cohort of ladies with pGDM in the Diabetes Prevention System trial.11 Furthermore more recent studies have shown that adherence to healthy diet patterns alone provides safety for T2DM risk in the pGDM population.12 13 Safety was most TOK-001 (Galeterone) considerable through the pattern characterized by the Alternate Healthy Feeding on Index (AHEI) demonstrating a 57% lower T2DM risk.12 The AHEI diet index created in 2002 evolved from the Healthy Feeding on Index as an alternative diet index to better forecast chronic disease risk.14 In addition to the T2DM risk reduction associated with AHEI adherence in ladies with pGDM the AHEI diet pattern has been associated with decreased risk for diabetes 12 15 lower risk for cardiovascular disease 16 cancer 17 and the reversal of metabolic syndrome in other populations.18 Identifying the factors that can be modified to improve adherence to the AHEI diet pattern is an important next step in mitigating risk reduction. Few studies have examined intrapersonal influences of diet quality in the pGDM populace and no study to date offers specifically examined the variables that may contribute to higher concordance with the AHEI diet pattern. The purpose of this study was to examine the association between the intrapersonal factors of socio-demographics depressive symptoms perceptions of T2DM risk benefits and barriers to healthy eating and self-efficacy with AHEI diet quality in ladies within five years of a GDM pregnancy. Theoretical Framework You will find multiple determinants that influence eating behavior and the quality of diet patterns. The determinants can be classified within contexts of intrapersonal interpersonal and environmental factors.19 Although this study focused on the intrapersonal determinants the investigators acknowledged the multiple contexts that influence dietary behavior and incorporated the ecological model TOK-001 (Galeterone) of eating behavior by Story and colleagues19 to frame the singular intrapersonal contextual focus. The variables examined in this study were specifically guided by the Health Belief Model to understand the intrapersonal factors of perceived threat of T2DM benefits and barriers to healthy eating and self-efficacy with AHEI diet quality (Number 1). Number 1 Intrapersonal Influences of Diet Quality in Ladies with pGDM Individual influences on healthy eating TOK-001 (Galeterone) have been widely analyzed among many populations and multiple intrapersonal factors have been associated with diet quality. As depicted in Story et al.’s ecological platform of the multiple influences of eating behavior the intrapersonal influences include cognitions skills and behavior way of life biological and demographics.19 Socio-demographic factors influence diet quality with most studies concluding that increased age higher education higher income and non-minority race/ethnicity are associated with higher diet quality.20-22 Knowledge and self-efficacy are important predictors of diet quality with post-partum and in women with pGDM.10 21 23 Major depression has also been TOK-001 (Galeterone) associated with lower diet quality 24 with some recent studies suggesting that poor diet quality may forecast depressive symptoms especially in women of childbearing age.25 26 The investigators of this study hypothesized that women with pGDM who experienced higher perceptions of the threat of T2DM along with higher perceived self-efficacy and benefits of healthy eating and lower perceptions of healthy eating barriers would have higher AHEI diet quality TOK-001 (Galeterone) controlling for socio-demographics dietary knowledge and depressive symptoms. Methods Study Design Establishing and Participants This was a cross-sectional descriptive quantitative study carried out from August 2011 through December 2012. Participants were recruited from the community and through women’s health clinics of an academic health center an inner-city general public hospital and a general public health division. Eligible participants were ladies who have been (a) within 5 years of a GDM pregnancy (b) aged 18-45 years (c) fluent in English or Spanish (d) with no history of polycystic ovary syndrome and no development of T2DM (e) not currently pregnant or breastfeeding (f) not.