Background Although there have been some studies focusing on the

Background Although there have been some studies focusing on the relationship between body mass index (BMI) coronary artery disease (CAD) and acute coronary syndrome the clinical effects of BMI about results after percutaneous coronary treatment (PCI) in individuals with acute myocardial infarction (AMI) are not well known inside a Taiwanese populace. group had a lower 30-day survival rate than the additional 3 groups and the underweight and normal weight patients experienced a lower 5-year survival rate than the obese and obese individuals. The multivariate regression analysis showed that Killip class ≥ 2 non-use of statin older age hemoglobin < 12 g/dl and chronic kidney disease but not BMI are self-employed predictors of all-cause mortality. Conclusions With this present study the major factors affecting long-term survival are lack of using statin and older age but not obese paradox. Keywords: Acute myocardial infarction Mortality Obesity Percutaneous coronary treatment Survival Obesity is definitely associated with improved morbidity and mortality and it is also associated with insulin resistance often resulting in diabetes mellitus hypertension and dyslipidemia.1-4 However additional previous studies suggested a trend called “obesity paradox” which meant that obese individuals had better results than normal-weight individuals after percutaneous coronary treatment (PCI).5-8 In the BARI study which enrolled individuals with stable angina and multi-vessel coronary artery disease (CAD) each unit increase in body mass index (BMI) was associated with a 5.5% lesser adjusted risk of a major in-hospital event but BMI was not associated with five-year mortality in the percutaneous transluminal coronary angioplasty group.6 Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality.9 However evaluating the risk stratification in patients with AMI remains demanding. 10-15 Obesity paradox was also found in individuals with acute coronary syndrome.16 17 However these available large-scale “obesity paradox” studies were largely based on the western populations not within the Asian populace and the follow-up periods of the studies enrolling individuals with acute coronary syndrome were usually less than 2 years. It is DAPT well-known the Asian populace is generally leaner than the western populace; therefore is the obesity paradox present in the Asian populace? Furthermore there have been few articles published addressing the relationship between obesity and long-term (more than 5 years) mortality. The medical effects of BMI on results after percutaneous coronary treatment (PCI) in individuals with acute myocardial infarction also remain unfamiliar in Taiwan. Consequently we intended to evaluate the medical effects of BMI within the results in AMI individuals after PCI in Kaohsiung Veterans General Hospital Taiwan. METHODS Study populace From January 2005 to December 2011 1491 consecutive AMI individuals were retrospectively examined. All patients were adopted up through March 2013. All living individuals had been adopted for at least 12 months. This retrospective study protocol was authorized by the Human being Study Committee of our hospital. Rabbit Polyclonal to Collagen I. The analysis of AMI was based on the Third Common Criteria of Myocardial Infarction18 and it should meet the detection of a rise and/or fall of cardiac biomarker ideals with at least one of the following: 1) symptoms of ischemia; 2) fresh or presumed fresh significant ST-segment – T wave changes or fresh left package branch block; 3) development of pathological Q waves in the ECG; 4) imaging evidence DAPT of new loss of viable myocardium or fresh regional wall motion abnormality; or 5) recognition of an intracoronary thrombus by angiography or DAPT autopsy. The inclusion criteria was AMI individuals who received PCI during hospitalization due to AMI and the exclusion criteria included DAPT individuals who ever received coronary artery bypass surgery AMI individuals who did not received PCI during the hospitalization due to AMI preexisting severe left-sided valvular heart diseases congenital heart diseases hypertrophy or dilated cardiomyopathy and individuals who had serious cardiogenic shock and died in the 1st 24 hours after presenting to our emergency room. Medical treatment of AMI individuals adopted the ACC/AHA ST-elevation and non-ST-elevation myocardial infarction recommendations.19-22 The coronary angiograms were performed by experienced cardiologists via Philips MultiDiagnost Eleva interventional radiography/fluoroscopy system. Following balloon dilatation the choice of bare-metal stent or drug-eluting stent deployment was dependent on the decision of operators. Body mass index Body mass index is definitely defined as an individual’s body weight divided from the square.